UT Health Science Center at San Antonio Cardiovascular Proteomics Center

Director: Merry L. Lindsey, PhD

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The goal of the UTHSCSA Cardiovascular Proteomics Center is to develop novel proteomic technologies to identify predictive markers of adverse remodeling of the left ventricle (LV) following myocardial infarction (MI), focusing on extracellular matrix (ECM) fragment generation as a key initiating event. The three major questions to answer during this contract period are:

• How does ECM proteins differentially produced and proteolytically processed post-MI temporally regulate the remodeling process?
• What are the best standard operating procedures to measure ECM at the proteome level and screen the functional consequence of altered ECM levels post-MI?
• Can ECM proteomics drive the development of better treatment strategies for the post-MI patient?

Links

http://www.barshop.uthscsa.edu/main/science/u43
http://www.linkedin.com/groups?gid=3775394
San Antonio Cardiovascular Proteomics Center Commercial

 

Publications

https://nhlbi.ctrl.ucla.edu/pages/publications