UT Health Science Center at San Antonio Cardiovascular Proteomics Center: Merry L. Lindsey, Ph.D.

Merry L. Lindsey, Ph.D.
Director, UTHSCSA Cardiovascular Proteomics Center
Director, San Antonio Center for Cardiovascular Systems Biology
UT Health Science Center at San Antonio
lindseym@uthscsa.edu

Our center is dedicated to performing cardiovascular research that involves:

Developing multidimensional approaches to examine the mechanisms whereby the left ventricle responds to injury;
Applying the knowledge gained to develop therapeutic strategies to prevent, slow, or reverse the progression to heart failure;
Disseminating our results to the general, scientific, and medical communities.

The Key Investigators

Seema Ahuja, M.D.	ahuja@uthscsa.edu
Robert J. Chilton, DO	chilton@uthscsa.edu
Youn-Min Chou, Ph.D.	younmin.chou@utsa.edu
John M. Erikson, MD, Ph.D.	erikson@uthscsa.edu
Gregg B. Fields, Ph.D.	gfields@tpims.org
Hai-Chao Han, Ph.D.	haichao.han@utsa.edu
Yufang Jin, Ph.D.	yufang.jin@utsa.edu
Richard A. Lange, M.D.	langera@uthscsa.edu
Susan T. Weintraub, Ph.D.	weintraub@uthscsa.edu

Selected Recent Publications

Heart Rate Reduction: An Old and Novel Candidate Heart Failure Therapy. Ma Y, Chilton RJ, Lindsey ML. Hypertension. 2012 May;59(5):908-10. Epub 2012 Apr 9. PMID: 22493078

Women are different: the role of coupling factor 6 in blood pressure regulation. de Castro Brás LE, Deleon KY, Lindsey ML. Hypertens Res. 2012 May;35(5):485-6. doi: 10.1038/hr.2012.9. Epub 2012 Feb 2. PMID: 22297476

Using extracellular matrix proteomics to understand left ventricular remodeling. Lindsey ML, Weintraub ST, Lange RA. Circ Cardiovasc Genet. 2012 Feb 1;5(1):o1-7. PMID:22337931

Proteomic analysis identifies in vivo candidate matrix metalloproteinase-9 substrates in the left ventricle post-myocardial infarction. Zamilpa R, Lopez EF, Chiao YA, Dai Q, Escobar GP, Hakala K, Weintraub ST, Lindsey ML. Proteomics. 2010;10:2214-23. PMID: 20354994

A conceptual cellular interaction model of left ventricular remodelling post-MI: dynamic network with exit-entry competition strategy. Wang Y, Han HC, Yang JY, Lindsey ML, Jin Y. BMC Systems Biology.2010: S5. PMID:20522255

CC Chemokine Receptor 5 Deletion Impairs Macrophage Activation and Induces Adverse Remodeling Following Myocardial Infarction. Zamilpa R, Kanakia R, Cigarroa J 4th, Dai Q, Escobar GP, Martinez HM, Jimenez F, Ahuja S, Lindsey M. Am J Physiol Heart Circ Physiol. 2011 Feb 4. [Epub ahead of print]. PMID:21297029.

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National Heart, Lung, and Blood Institute

National Institutes of Health

Department of Health and Human Services